Adam Cayton-Holland (born June 2, 1980) is an American stand-up comedian from Denver, Colorado best known for his work with the comedy trio The Grawlix and their sitcom television series Those Who Can't.

[2] That same year he was invited to the prestigious New Faces competition at Montreal's Just for Laughs Comedy Festival, appeared on the Nerdist podcast, and had a cameo on the ABC show Happy Endings (TV series).

The trio produces a monthly show at The Bug Theater in Denver, featuring standup sets from each of the principals and a variety of national guest comedians.

Past shows also included regular screenings of their self-entitled web series, which was produced and directed by The Nix brothers.

The trio emerged from "Los Comicos Super Hilariosos," a comedy show created by Cayton-Holland with fellow comedians Greg Baumhauer, Ben Roy, Jim Hickox, and Andrew Orvedahl.

During its run, "Los Comicos" welcomed big-name comics like Arj Barker, Maria Bamford, Tig Notaro, and Moshe Kasher.

[8] In June 2012, The Grawlix teamed with The Nix Brothers to produce a television pilot called Those Who Can't, a sitcom about three inept Denver high school teachers, for Amazon Studios.

It’s an honest look at mental illness, depression, death and the beautiful relationships between families and siblings — one that lets you know that there is no guide to grief, and that it’s still O.K.

In its inaugural year, the Festival ran three days in venues throughout Denver, and featured both local and national talent—including headliner Reggie Watts, Matt Braunger, and Kyle Kinane.

In recognition of his work on the play, Cayton-Holland received the 2019 True West Award from the Denver Center for the Performing Arts.

[22] The central concept of the podcast was Cayton-Holland's loyalty to and love of Denver and his home (hence, the majority of the recordings took place at his actual dining room table), and his subsequent decision to stay in the city rather than move to LA or New York.

He interviewed local and national comics and musicians about a variety of topics, but often returned to the core ideas of "home" and "success" while promoting the burgeoning Denver cultural scene.