[5] Milstein is a managing partner of Hager Pacific Properties, overseeing the firm's financing, disposition and accounting.

[18] Milstein strongly opposes the Boycott, Divestment and Sanctions (BDS) Movement,[19][20] and has had several op-ed pieces published on this subject.

[21][22] Milstein and his wife Gila are co-founders of Sifriyat Pijama B'America, which provides free monthly books in Hebrew to Israeli-Jewish American families in the United States.

[9] In 2016, they started "The Impact Forum", an initiative which "fights antisemitism, strengthens the state of Israel, and protects American democracy.

[1][25] In 2015 and 2016, Algemeiner Journal named Milstein to its list, "The Top 100 People Positively Influencing Jewish Life.

"[26][27] Gil Troy identifies Milstein as a contemporary leader of cultural Zionism in his book The Zionist Ideas: Visions for the Jewish Homeland—Then, Now, Tomorrow (2018).

"[28] In 2019, Milstein withdrew from speaking at that year's AIPAC conference after he posted tweets seeking to connect Ilhan Omar and Rashida Tlaib to the Muslim Brotherhood.