Admiral Colpoys first appears in Lloyd's Register for 1801 with Disney, master, Atkins & Co. as owners, and London-Bermuda as trade.

1st voyage transporting enslaved people (1801–1802): under George Adams, master, Admiral Colpoys left London on 17 November 1801.

[7] In 1801, 147 vessels left English ports, bound on voyages to transport enslaved people; 23 sailed from London.

[9] 2nd voyage transporting enslaved people (1804–1805): under Henry Coley, master, Admiral Colpoys left London on 2 October 1804, bound for the Gold Coast.

[10] In 1804, 147 vessels left English ports, bound on voyages to transport enslaved people; 18 sailed from London.

[8] Admiral Colpoys started acquiring captives at Cape Coast Castle and then Accra, beginning on 7 February 1805.

[10] 3rd voyage transporting enslaved people (1807–1808): on 20 January 1807 Richard Coaley received a letter of marque for Admiral Colpoys.

[12] "The Subscribers inform their Friends who Commissioned them to Purchase Negroes in Barbados, that they have received by the Ship Admiral Colpoys, Capt.

""The Subscribers beg leave to inform such of their Friends as Commissioned them to import Negroes, that they have just received 90 Prime Young Gold-Coast Slaves, being part of the Cargo of the Ship Admiral Colpoys from cape coast, last from Barbados, which will be ready for delivery on Saturday the 10th Instant, at the Store of John Madden, Esq.

Lloyd's Register for 1810 shows Admiral Colpoys with Venables, master, King & Co., owners, and trade London-Demerara.

She had left St Helena on 5 March 1815 in company with Indian Oak and Lady Nugent, both trading with India under a license from the EIC.