The generic name combines the Greek word ἀήρ, meaning "air" and Titan, alluding to the pterosaur's large size.

Within Azhdarchidae, the genus Mistralazhdarcho from France seems to have been the closest relative of Aerotitan, based on numerous phylogenetic analyses that have recovered them together in a clade.

The only specimen of Aerotitan is MPCN-PV 0054, which has been recovered near the Bajo de Arriagada site from a layer of the upper Allen Formation in Patagonia, Argentina.

The generic name Aerotitan is a combination of the Greek word ἀήρ, aer, meaning "air", and Titan, in reference to the fact that the species represents a large flying reptile.

[1] However, in 2018, a study published by paleontologist Nicholas Longrich and colleagues classified Aerotitan as a member of the family Thalassodromidae, being the sister taxon of Alanqa (a pterosaur also assigned as an azhdarchid in its initial description).

Azhdarcho lancicollis Albadraco tharmisensis Aerotitan sudamericanus Mistralazhdarcho maggii Aralazhdarcho bostobensis Phosphatodraco mauritanicus Eurazhdarcho langendorfensis Zhejiangopterus linhaiensis Wellnhopterus brevirostris Cryodrakon boreas Hatzegopteryx thambema Arambourgiania philadelphiae Quetzalcoatlus lawsoni Quetzalcoatlus northropi Cladogram by Pêgas and colleagues (2023).