Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana.

[1][2] Structurally, it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction.

[3][4] Limited pharmacological testing has indicated that affinisine may effectively inhibit acetylcholinesterase and butyrylcholinesterase.

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