[5][6] AFEM aims to strengthen emergency care in Africa by leading collaborations and prioritizing health advocacy.

By using strategic research agendas, AFEM has provided guidance for education and training, and facilitated the development of sustainable policies and frameworks to strengthen emergency care.

[6] One author has said, "[AFEM] has produced the most concrete solutions responsive to the action items laid out in [World Health Assembly] 60.22.

During the COVID-19 pandemic the federation promoted Surgisphere's COVID-19 Severity Scoring Tool for use in 26 African countries.

On 5 June 2020, in response to a scandal uncovering academic misconduct by Surgisphere, the federation recommended that use of the severity scoring tool be ceased.