Established in the early 1800s as a trading post with the Choctaw people, the community today is a rural crossroads.

Agency began as a government trading post established to maintain contact with the Choctaw people.

Ward's house fronted the north side of Robinson Road, and consisted of two large rooms made of hewn logs.

[3] The Choctaw council house was situated on the east bank of Noxubee river, about 2.5 mi (4.0 km) southeast of Agency, just north of the county line.

[2] Agency had a school,[5] a post office by 1854,[6] a Masonic Grand Lodge from 1861 to 1872,[7] and one of Oktibbeha County's three "dens" of the Ku Klux Klan.