Four non-coding small RNAs containing a Fur box-like (ferric uptake regulator) sequence were identified by bioinformatics analysis in Aggregatibacter actinomycetemcomitans HK1651 called JA01-JA04.
Fur binding was demonstrated to each sRNA promoter, and that transcription of the sRNAs was decreased in presence of iron and increased by iron limitation.
JA 03 and JA04 are most widely conserved and have orthologues across many Pasteurellaceae.
HrrF RNA is another Fur-regulated sRNA conserved among the Pasteurcellaceae.
[2] This molecular or cell biology article is a stub.