HrrF DNA (Haemophilus regulatory RNA responsive to iron Fe) is a small non-coding RNA involved in iron homeostasis in Haemophilus species.

HrrF is maximally expressed when iron levels are low.

Ferric uptake regulator (Fur) binds upstream of the hrrF promoter.

HrrF stability is not dependent on the RNA chaperone Hfq.

RNA-seq has shown that HrrF targets are mRNAs of genes whose products are involved in molybdate uptake, deoxyribonucleotide synthesis, and amino acid synthesis.