The relevant infectious agent may be viruses, bacteria, or fungi, and they may be spread through breathing, talking, coughing, sneezing, raising of dust, spraying of liquids, flushing toilets, or any activities which generate aerosol particles or droplets.
[8] Larger droplets greater than 100 μm usually settle within 2 m.[8][5] Smaller particles can carry airborne pathogens for extended periods of time.
Two examples are the bacterias Yersinia pestis (which causes plague) and Francisella tularensis (which causes tularaemia), which both can cause severe pneumonia, if transmitted via the airborne route through inhalation.
Airborne transmission is complex, and hard to demonstrate unequivocally[20] but the Wells-Riley model can be used to make simple estimates of infection probability.
[25][26] The transmission of airborne diseases is affected by all the factors that influence temperature and humidity, in both meteorological (outdoor) and human (indoor) environments.
Circumstances influencing the spread of droplets containing infectious particles can include pH, salinity, wind, air pollution, and solar radiation as well as human behavior.
[27] Airborne infections usually land in the respiratory system, with the agent present in aerosols (infectious particles < 5 μm in diameter).
A layered approach can include interventions by individuals (e.g. mask wearing, hand hygiene), institutions (e.g. surface disinfection, ventilation, and air filtration measures to control the indoor environment), the medical system (e.g. vaccination) and public health at the population level (e.g. testing, quarantine, and contact tracing).
[4] Preventive techniques can include disease-specific immunization as well as nonpharmaceutical interventions such as wearing a respirator and limiting time spent in the presence of infected individuals.
[45][4][46] Portable air filters, such as those tested in Conway Morris A et al. present a readily deployable solution when existing ventilation is inadequate, for instance in repurposed COVID-19 hospital facilities.
[48] A 2011 study concluded that vuvuzelas (a type of air horn popular e.g. with fans at football games) presented a particularly high risk of airborne transmission, as they were spreading a much higher number of aerosol particles than e.g., the act of shouting.
[50] In addition the risk for infection is also dependent on host immune system competency plus the quantity of infectious particles ingested.