Akosua Frema Osei-Opare (born, June 5, 1947) is a Development Practitioner, an Academic, Economist and a Ghanaian politician.

Having spent 40 years in these domains, Akosua Frema Osei-Opare, is an expert in labour and hiring as well as development consulting.

She has also worked with the United Nations in the Women In Fisheries project in various capacities in Uganda, Ethiopia, Congo and Namibia.

[11] Frema in 2005 - 2008 worked under the government of President John Agyekum Kufuor as the Deputy Minister for Manpower, Youth and Employment.

[12] On Friday, July 7th, 2023, The Valley View University bestowed an honorary Doctorate Degree upon Akosua Frema Osei-Opare, the Chief of Staff, in recognition of her exceptional accomplishments and unmatched contributions to the advancement of Ghana.

"[13] On Sunday, March 3, 2024, at the Jubilee House, Akosua Frema Osei Opare, Chief of Staff of the Republic of Ghana, threw an exclusive event for representatives of the Black Queens.

She served a two term office as the member of parliament representing Ayawaso West Wuogon Constituency between 2005 and 2013 under the ticket of the NPP.