In January 2017, he signed a three-and-a-half-year deal at Vitória de Guimarães of Portugal's Primeira Liga, on the recommendation of their former player Romano Sion.

[4] Thirteen days later he made his Primeira Liga debut in a 1–1 home draw with Boavista and was third-place in the vote for the league's best midfielder of the month, behind Bruno Fernandes and Pizzi.

[5] On 12 December, he scored his only goal for the first team, equalising in a 3–2 comeback win at Eintracht Frankfurt in the group stage of the UEFA Europa League; his club was already eliminated.

[9] His first goal was on 26 November, to open a 3–3 home draw with Leicester City in the Europa League group stage;[10] three days later he struck for the first time in the top flight to win at the Estádio Municipal de Braga against Farense.

[22] Al-Musrati was first called up for Libya at the 2014 African Nations Championship in South Africa, and played all but one game including the penalty shootout win over Ghana in the final.