[2] It travels to the north-northeast and has an intersection with Geneva County Route 4 (CR 4; Fink Mill Road).

After two crossings of Poplar Branch, it begins a concurrency with Geneva CR 10.

After the highways split, SR 153 curves to a nearly due north direction and crosses over Flat Creek.

The highway curves to the north-northwest and intersects the southern terminus of Geneva CR 17 (Columbus–Holley Road).

It curves to a nearly due north direction and meets its northern terminus, an intersection with SR 52 west of Samson.