The southern terminus of the highway is at an intersection with U.S. Route 31 (US 31) just north of Jemison.

The northern terminus of the highway is at an intersection with SR 119 in Montevallo.

From its beginning at Jemison, SR 155 travels in a northwestward direction as it leaves Chilton County.

Southeast of Montevallo, the highway has an intersection with SR 25 and turns west, forming a brief wrong-way concurrency.

The northern terminus of the highway is at an intersection with SR 119 near the entrance to the campus of the University of Montevallo.