Alberto Castagna started working as a journalist for the newspapers Il Piccolo and Settimanale.

[2] After winning a Telegatto as "personaggio maschile dell'anno", in 1993 he left RAI network switching to Fininvest, where he hosted the afternoon quiz Sarà vero?, aired by Canale 5.

In the same year he suffered a double aneurysm; because of this he stayed in the hospital from July 18, 1998, to March 1999,[6] attracting the attention of the Italian media because of his critical state of health.

[7] In 1999 he also released for Arnoldo Mondadori Editore the biographical book La mano sul cuore.

[10] In February 2005, Alberto Castagna started presenting a new edition of Stranamore, with Emanuela Folliero, but it was never completed because of his death, which occurred on 1 March 2005 due to an internal bleeding.