Alchornea castaneifolia (iporuru, iporoni, iporuro, ipururo, ipurosa, macochihua, niando, pajaro; syn.

For centuries the indigenous peoples of the Amazon have used the bark and leaves of iporuru (Alchornea castaneifolia) for many different purposes and prepared it in many different ways.

The Candochi-Shapra and the Shipibo Indian tribes use both the bark and roots of iporuro for rheumatism.

[citation needed] To prevent diarrhea, members of the Tikuna tribe take one tablespoon of Alchornea castaneifolia bark decoction before meals.

Initial screening has revealed it to contain steroids, saponins, alkaloids and natural phenols (flavonols, flavones, tannins, xanthonoids).