Ayo, a native of Sorsogon City, graduated from Colegio De La Milagrosa in elementary and finished his high school education at the Our Lady of Peñafrancia Seminary in 1994.
[11] In 2015, even with a small lineup yet applying pressure mayhem defense and relentless run and gun offense, he led the Knights to win the NCAA Championship since 2005 and dethrone their archrivals, the erstwhile five-time champion San Beda Red Lions.
One year after taking over as head coach, Ayo led the UST Growling Tigers to the UAAP Season 82 Men's Basketball Finals by winning against the FEU Tamaraws and UP Fighting Maroons in the stepladder semifinals before meeting the Ateneo Blue Eagles.
The Growling Tigers eventually lost in two games to the Blue Eagles, who completed a 16-game winning streak and won their third straight UAAP Men's Basketball Championship title under head coach Tab Baldwin.
[17][18][19][20][21][22][23][24] On September 4, 2020, Ayo resigned as Growling Tigers head coach due to him holding practices with the team in Sorsogon amidst the COVID-19 pandemic which violates the quarantine protocols set by the Philippine government.
The resulting controversy led to the departure of some of the players from UST namely CJ Cansino, Rhenz Abando, Brent Paraiso, Ira Bataller, and Jun Asuncion.
[25] As a result of this, the UAAP imposed an indefinite ban on Ayo which prevents him from taking any future role within the collegiate league.