Mazzucotelli was born in Lodi to Giovanni Valente, an iron merchant originally from Locatello di valle Imagna, and Rosa Caprara.

Mazzucotelli collaborated with architects such as Enrico Zanoni,Giuseppe Sommaruga, Gaetano Moretti, Ernesto Pirovano, Franco Oliva, Ulisse Stacchini and Silvio Gambini.

[5] In 1902 he distinguished himself at the first International Exhibition of Modern Decorative Art in Turin; Charles Rennie Mackintosh, Louis Comfort Tiffany and Peter Behrens participated in it.

His activity intensified after the opening of his new company in Bicocca, in 1909, where he began to work with South American clients and to intervene on celebratory buildings such as the Expiatory Chapel in Monza, the city named a street after him.

In 1922 he founded and directed the Istituto Superiore per le Industrie Artistiche (ISIA) in Monza, where he had as a student and successor to the chair of wrought iron Gino Manara; he was president of the International Biennial Exhibition of Applied Arts in 1923 where he presented the gate "Groviglio di serpi".