Alessandro, Principe Ruspoli (December 3, 1708 – June 20, 1779) was the 2nd Principe di Cerveteri, 2nd Marchese di Riano and 7th Conte di Vignanello.

He was the son of Francesco Maria Marescotti Ruspoli, 1st Prince of Cerveteri and his wife Isabella Cesi dei Duchi di Acquasparta, maternal niece of Pope Innocent XIII.

He married firstly in 1720 as her first husband Virginia Altieri dei Principi di Oriolo (Rome, May 6, 1705 – ?

The marriage was annulled by the Pope.

He married secondly in 1749 his first cousin Prudenza dei Conti Marescotti-Capizucchi, daughter of his uncle Mario, 1st Conte Marescotti-Capizucchi (1681 – December 23, 1758) and wife Cassandra Sacchetti dei Marchesi di Castel Rigattini, and paternal granddaughter of Alessandro Marescotti, 5th Conte di Vignanello and second wife Prudenza Gabrielli (December 17, 1654 – December 13, 1709), by whom he had six children: