In the late 2010s, she starred as Juliana Crain, the main character in the Amazon Studios series The Man in the High Castle.

[11] She also played Sally in The Mist (directed by Frank Darabont), co-starring Thomas Jane, Laurie Holden and Marcia Gay Harden.

In 2008, Davalos co-starred as the love interest of Daniel Craig in the war film Defiance, directed by Edward Zwick.

[10] Davalos played Andromeda in the remake of Clash of the Titans, alongside Sam Worthington, Ralph Fiennes and Liam Neeson.

[14] In addition to her film roles, she also continued to appear in television series, including Reunion (2005–2006) and Mob City (2013).

[13] In 2015, Davalos started acting in The Man in the High Castle (2015–2019), an Amazon Studios series based on the Philip K. Dick novel of the same name.

Starring as Juliana Crane, the main character of the series, she played the biggest role of her career up to that point.

In the early 2020s, Davalos had a regular role in two seasons of the CBS crime series FBI: Most Wanted as Special Agent Kristin Gaines.