She became a slave ship in the triangular trade in enslaved people, sailing from Liverpool.

Alexander returned to British ownership and became a West Indiaman, and then a transport.

[1] Captain Robert Pince sailed from Liverpool on 10 June 1806 to acquire captives in West Africa.

She may have been the "English Ship Alexander, laden with Indigo, Cotton, Copper, and Dry Wood" that the Royal Navy captured in the harbour on 21 December 1807 when the Danish island of Saint Thomas capitulated to the forces under Rear-Admiral the Honourable Sir Alexander Cochrane.

[10] Alexander, Surflen, master, last appeared in Lloyd's List's ship arrival and departure data as sailing from Cork on 18 January 1815, bound for Bermuda together with a number of other vessels.