She emigrated to the United States in 1935, where she worked as a neurology instructor at the Harvard Medical School.
[5] From 1928 to 1938, Alexandra Adler conducted an investigation of known cases of encephalitis or encephalomyelitis at the Boston City Hospital.
[6] The study was conducted on the brain of a patient with multiple sclerosis, resulting in new information on how the disease affected the human body.
[6] In the 1950s and throughout the 1960s, Adler continued her father's work of Adlerian psychology for possible treatments for schizophrenia, neuroses, and personality disorders.
She believed this could be done through modern drug treatment, group therapy, and the existentialist and religious psychotherapies.