As a student, at Zappeio Girls School in Istanbul, she was influenced by an exceptionally fertile cultural environment with notable works of art which encouraged her to develop an aesthetic and artistic foundation.
In 1936, Dimitris Pikionis, professor of National Technical University and supervisor of the project concerned with the study and the analysis of the architecture and decorative arts of Greek housing, assigned the completion of that project to a team of young architects: Dimitris Moretis, Giorgos Giannoulelis and Alexandra Paschalidou.
The collected material was first presented in 1938 at the Stratigopoulou venue and at Zappeion, however because of the Second World War, the programme had to be discontinued.
In 1939, the Ministry of Press and Tourism assigned to Alexandra Paschalidou-Moreti and Dimitris Moretis the design of the Greek Pavilion for the New York World’s Fair.
In 1951, she worked as an architect for the General Secretariat of Tourism to facilitate and organize the reconstruction of the devastated facilities of the National Exhibition Center of Thessaloniki.
In the same capacity, she visited many places in Greece where she documented and photographed destruction from the War and the German occupation.
In addition Paschalidou-Moreti and Dimitris Moretis undertook studies and designed touristic installations for a variety of purposes such as hotels, hostels, hiking stations, mountain huts and spa facilities.
She showed particular interest in studying the architecture of the islands of Kefalonia, Siros, Tinos, Naxos and Paros.
Alexandra Paschalidou-Moreti published articles and studies concerned with Public Art, interior design and National and International Exhibitions.
In addition, she gave many interviews in the media (press, radio, television) primarily concerning the role of women and Greek architecture, both new and traditional.
Alexandra Paschalidou-Moreti received the Award of the Universal Exhibition of Berlin in 1938 and was made an “Honorary Citizen of the State of New York” in 1939.