Alexandre de Rhodes, SJ (French pronunciation: [alɛksɑ̃dʁ də ʁɔd]; 15 March 1593[1] – 5 November 1660), also Đắc Lộ was an Avignonese Jesuit missionary and lexicographer who had a lasting impact on Christianity in Vietnam.

In 1624, he was sent to the East Asia, arriving in the Nguyễn-controlled domain of Đàng Trong (known to the Europeans as Cochinchina) on a boat with fellow Jesuit Girolamo Maiorica.

Following the successful visit of fellow Jesuits Giuliano Baldinotti and Julio Koga to Đàng Ngoài (Tonkin) in 1626, the superior André Palmeiro sent Alexandre de Rhodes and Pero Marques, Sr. to evangelize in this domain of North Vietnam.

During these three years he was in and around the court at Hanoi during the rule of lord Trịnh Tráng, where he captivated the emperor with gifts such as an intricate clock and a glided volume on mathematics.

De Rhodes compiled a catechism, "Catechismus pro ijs, qui volunt suscipere baptismum in octo dies divisis", and a trilingual dictionary and grammar, Dictionarium Annamiticum Lusitanum et Latinum.

Meanwhile, Maiorica's catechism and devotional texts reflect the favor of chữ Nôm, which was the dominant script of Vietnamese Christian literature until the 20th century.