Alfie Alfandy received his first lead role in the film, Hijrah Cinta, where he portrayed Indonesian Islamic preacher Jefri Al Buchori, also known as "Uje".

[6] In the 2023 film Buya Hamka, Alfie played the role of Dadang, a prison warden who guarded the titular Indonesian preacher.

[8] In 2017, Alfie sang "Syukuri Ujian-Mu" (written by Antrabez) as the theme song for the eleventh season of the Para Pencari Tuhan TV series and released it as a single.

[12] In 2023, Alfie released a pop indie mini album titled Generasi Berfikir (English: Thinking Generation) and consisting of five songs written by himself.

[16] After studying in Darul Musthofa Yaman, Alfie founded a motorcycle club, Bikers Dakwah, as a way to do dawah while doing his hobby.