Alfred Kwame Agbesi (born 20 February 1955) is a lawyer and politician in Ghana.

He holds Bachelor of Laws degree from the University of Ghana, Legon in 1979 and BL (GSL) 1981.

[2] Alfred Agbesi was the member of Ghana's parliament for Ashaiman Constituency from 2005 up till 2016 when he lost to the current member of Parliament for the Ashaiman constituency Ernest Norgbey in the Primaries of the National Democratic Congress in 2015.

He was elected over Hajia Hajara M. Ali of the People's National Convention, Teye Emmanauel Kinsford Kwesi of the New Patriotic Party, Phoyon Isaac Bruce Mensah of the Convention People's Party and Amable Kwame Samuel am independent candidate.

[8] In all, the National Democratic Congress won a total 94 parliamentary seats in the 4th parliament of the 4th republic of Ghana.