Alias was the basis of the first season of the Netflix Marvel Cinematic Universe (MCU) series Jessica Jones, which premiered in November 2015.

Bendis relates in a text piece on the letters page of the book's final issue that it was one of the reasons the imprint was created.

Bendis gave this as one reason for ending the series and moving the characters to The Pulse, retroactively setting Alias in the mainstream Marvel continuity of Earth-616.

[1] In a 2005 interview, Bendis revealed that originally, Alias was plotted to be an explicitly out-of-continuity story following a reinvention of superhero private investigator Jessica Drew returning to her P.I.

[3] Previously, Bendis commented:[4] Some of the flashbacks to Jessica Jones's past are drawn in the style of classic 1960s, 1970s, 1980s and 1990s Marvel Comics issues.

[citation needed] Tasked to look for a missing woman, Jessica finds herself caught in a conspiracy involving Captain America and the President of the United States.

[8] Both issues depict the same scene, in which a disguised Natasha Romanova visits Matt Murdock at his law office, from two different perspectives.

In the course of her investigation she discovers that Mattie is embroiled in a criminal underworld producing Mutant Growth Hormone, a drug designed to give ordinary people super-powered abilities.

Meanwhile, Jessica's relationship with Scott Lang becomes strained after an encounter with Madame Web dredges up bad memories from her past.

[11] Issues #22-23 depict Jessica's teenage years, revealing that she attended Midtown High School with Peter Parker, whom she secretly had a crush on and was present when he was bitten by the spider that gave him his powers.

Jean Grey helped Jessica awaken from her resulting coma, and implanted a psychic defense in her mind in case of future encounters with the Purple Man.