[3] Huke earned a bachelor's degree in mathematics from Mount Holyoke College in 1924.

[5] Her doctoral advisor was Gilbert Ames Bliss, who oversaw her 1930 dissertation, "An Historical and Critical Study of the Fundamental Lemma in the Calculus of Variations".

She taught mathematics at Mount Holyoke College from 1929 to 1930, and at the Pennsylvania State University, part time after she married and full-time after 1947, two years after her last child was born.

[3][8] In addition to her teaching, Frink translated a Russian-language mathematical text, Calculus of Variations by Naum Akhiezer, published in 1962.

[10] She was a charter member of the Women's Scientific Club at Penn State, along with Pauline Gracia Beery Mack, Mary Louisa Willard, and Teresa Cohen; the club became a chapter of Sigma Delta Epsilon (now Graduate Women in Science).