After a curating stint at the British School at Rome, Jacques teamed up with Charles Asprey, and in 1998 they opened their gallery, which ran for seven years.
In 2023, the gallery announced plans to move into a three-storey, 560 m2 (6,000 sq ft) space on Cork Street which had previously been inhabited by Lisson Gallery on a temporary contract and was later refurbished by the architect Mike Rundell.
[2] The gallery often holds events and talks in conjunction with the exhibition programme, hosted by curators and critics.
Since opening her own gallery in 2004, Jacques has developed an exhibition program of both unknown and established artists: The gallery also represents the estates of several artists, including: Notably, Jacques has worked with the estate of Robert Mapplethorpe since 1999, starting when she was in partnership with Asprey.
Eddy Frankel said, "This Fitzrovia gallery has some serious art clout, representing the estates of Robert Mapplethorpe and Ana Mendieta.