[2] In a 2023 interview on The Howard Stern Show, Earle stated that she initially attempted to fulfill an idealized, perfect persona.

"[17]: 1:00 Earle's growth on TikTok accelerated in the summer of 2022, when she was affected by acne stemming from an excessive facial cyst.

[18][19] Upon its debut, Hot Mess with Alix Earle briefly unseated The Joe Rogan Experience from the top position on Spotify's podcast charts, a spot it had occupied for two years.

[21] In June 2024, Earle appeared in the music video for the single "Girls" by Australian artist The Kid Laroi.

[22] Earle dated Tyler Wade, a professional baseball player for the San Diego Padres, for three months in late 2022.

[23][24][25] In October 2023, Earle spoke publicly about her struggles with an eating disorder and body dysmorphia during high school.