[4][5] The foundation conference of the AISF was held at Ganga Prasad Memorial Hall in Lucknow, with 936 delegates from across India.

The conference resolved to establish an All India Students' Federation, and Prem Narayan Bhargava was elected as the first general secretary.

Hemu Kalani, an AISF leader, was arrested by the British army in 1942 for leading the Quit India Movement, and publicly hanged in 1943 at the age of 19.

[8] During the Royal Indian Navy mutiny in Bombay in February 1946, the AISF helped to mobilise students in support of the Naval Ratings.

[7] After independence, the AISF concentrated its activities mainly on educational issues, anti-imperialism and anti-feudalism, providing a platform for student unity against common threats.

[11] The AISF participated in the Kothari Commission report, which provided the basis for broad educational reforms in India.

[40] The administrative structure of the federation includes: [42]Viraaj Devang At the 30th AISF National Conference, held in September to October 2023 in Begusarai, Bihar, Vicky Mahesari from Punjab was elected as National President and Dinesh Seerangaraj from Tamilnadu was elected as General Secretary.