Aloe mayottensis (previously Lomatophyllum mayottensis) is a species of Aloe indigenous to the island of Mayotte and surrounding islands of the Comoros, in the Indian Ocean.

[1] It is part of a group of aloes which bear fleshy berries, and were therefore classed as a separate group, Lomatophyllum.

Within this group, it is a relatively distinctive and easily recognisable species.

Its leaves are a green with pale yellow brown margins and teeth.

Its multi-branched inflorescence bears flowers in racemes, and its seeds develop in fleshy berries.