α-Hederin

α-Hederin (alpha-hederin) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa and leaves of Hedera helix.

[1][2][3][4] α-Hederin and also its derivative, kalopanaxsaponin-I, have been studied for their anticancer activities.

[5][2] α-Hederin has been shown to enhance the cytotoxicity of an established chemotherapeutic agent, 5-fluorouracil, in an animal model of colon carcinoma.

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