It began an Off Broadway run on March 1, 2005, and closed on January 10, 2010, after sixteen previews and 2,032 regular performances, making it the 9th longest-running Off-Broadway musical of all time.

Four of the group's members, Matthew ("the leader"), Mark ("the sensitive one"), Luke ("the bad boy") and Juan ("the Latin Lover"), apparently are named after the authors of the four canonical Christian Gospels.

The members of the group address the audience directly and refer to the venue and location in which the performance is taking place.

The five Boyz proceed to perform biased skits based on what they remember of the band's formation.

Matthew remembers having trouble writing a song for the retirement party of Father Lucas, a priest at the church he attended.

Matthew is the leader, Mark is the choreographer, Juan picks out the clothes, Abraham is the songwriter, and Luke drives the tour van.

Then, Abraham sings his song, claiming that it doesn't matter who you are, but that you belong in God's family nonetheless (Everybody Fits).

The Boyz try to continue the set list like normal, but Juan begins to cry and grieves his family.

Abraham takes his place in singing his big song, but gives up on the dance break and attempts to search for Juan, who has run away and is trying to leave the theater.

When the Boyz get him back, he regains his confidence and continues his song with pride (La Vida Eternal).

As Luke tries for an encore, Matthew stops the Boyz, and shamefully admits that he has signed a solo deal, and will be leaving the band.

The NYMF cast included Cheyenne Jackson as Matthew, Tyler Maynard as Mark, Andy Karl as Luke, Ryan Duncan as Juan, and David Josefsberg as Abraham.

Due to the nature of the festival, the NYMF run was limited to eight performances on an irregular schedule over the course of a few weeks.

The production closed on January 10, 2010, after 2,032 regular performances, making it the ninth longest-running Off-Broadway musical of all time.