Alternariol (commonly abbreviated as AOH) and his monomethylether AME is a toxic metabolite of Alternaria fungi.
[2] Alternariol exhibits antifungal and phytotoxic activity.
A 2017 in vitro assay study reported alternariol to be a full androgen agonist.
[4] The acute toxicity of AOH and AME is low, but in vitro the substances show a strong mutagenic and teratogenic effect.
The substances are associated with the development of esophageal cancer[5].