From 1921 to 1923, he held the post of Minister of Foreign Affairs in the Rada of the Belarusian Democratic Republic in exile and chaired the First All-Belarusian Conference in Prague in September 1921.

[3][4][5] At the Second All-Belarusian Conference in Berlin in 1925, influenced by the successes and achievements of the policy of Belarusianisation in the BSSR, Ćvikievič decided to recognise Minsk as the only centre of the Belarusian national revival.

He worked in the People's Commissariat of Finance and as a scientific secretary at the Institute of Belarusian Culture [be-tarask], predecessor of the Academy of Sciences.

In July 1930, he was arrested and charged in the Case of the Union of Liberation of Belarus and in April 1931 sentenced to 5 years in exile in Russia.

[6][5] Ćvikievič's most important historical works have been dedicated to studying the idea of Westrussianism [be-tarask], which he described as an instrument of cultural assimilation of Belarusians.

[7] In his primary monograph, "Westrussianism: Essays on the History of Public Thought in Belarus in the XIX and early XX centuries" (Belarusian: Западно-руссизм: Нарысы з гісторыі грамадзкай мысьлі на Беларусі ў XIX і пачатку XX в.; Minsk, 1929), he analysed the ideology and practice of Russification of Belarus during the Russian Empire.