The American Journal of Human Genetics is a monthly peer-reviewed scientific journal in the field of human genetics.

It was established in 1948 by the American Society of Human Genetics and covers all aspects of heredity in humans, including the application of genetics in medicine and public policy, as well as the related areas of molecular and cell biology.

[2] According to the Journal Citation Reports, the journal has a 2019 impact factor of 10.502.

[3][4] The journal is published by Cell Press an imprint of Elsevier.

Bruce R. Korf became the editor-in-chief in the winter of 2017–2018.