[19] Sindhu along with Arfana Mallah started chapter of Women's Action Forum in Hyderabad in 2008.

[20][21][22] Sindhu was inspired by Sabeen Mahmud's T2F in Karachi,[23] and she along with Haseen Shah and Arfana Malah started the "Khanabadosh Writers Cafe"[24] at the Sindh Museum to offer a space where intellectuals and creative people from Hyderabad and other areas of Sindh can engage in intellectual discussions.

[26] Those who paid homage included veteran politician Rasool Bux Palijo and writer, Noorul Huda Shah.

[33][34] She also published a magazine named Adrish[35] on social, political and cultural issues.

[38] Sindhu has written many articles about the poetry of Shaikh Ayaz, a legendary poet of Sindh.