His first role on a feature film was in Takeshi Kitano's Brother, along others as "Orange Julius" in Universal's 2 Fast 2 Furious.

Nolasco's additional television and film credits include roles on George Lopez and CSI: NY, and in The Benchwarmers.

Bay offered to cast Nolasco in the sequel Transformers: Revenge of the Fallen, but he declined due to scheduling conflicts.

In November 2009, Nolasco made an appearance in Wisin & Yandel's music video "Imagínate" featuring T-Pain alongside Wilmer Valderrama.

Nolasco was featured in the sitcom Telenovela, as Rodrigo Suarez, Ana Sofia's eccentric co-star who plays the show's villain.