Ambroxide, widely known by the brand name Ambroxan, is a naturally occurring terpenoid and one of the key constituents responsible for the odor of ambergris.
[2] Ambroxide is used in perfumery for creating ambergris notes and as a fixative.
[2] Small amounts (< 0.01 ppm) are used as a flavoring in food.
[3] Ambroxide is synthesized from sclareol, a component of the essential oil of clary sage.
[4] Sclareol is oxidatively degraded to a lactone, which is hydrogenated to the corresponding diol.