The American Journal of Health-System Pharmacy is a biweekly peer-reviewed medical journal covering all aspects of drug therapy and pharmacy practice specific to hospitals.

It was established in 1943 and is published by the American Society of Health-System Pharmacists.

The journal was founded in 1943 as the Bulletin of the American Society of Hospital Pharmacists.

Its sponsoring society launched a second journal, Clinical Pharmacy, in 1982; the two publications merged in 1994.

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