American Samoa competed at the 2012 Summer Olympics in London, United Kingdom from July 27 to August 12, 2012.

Five athletes from American Samoa were selected to the Games; all of them were given under Universality slots and tripartite invitation, without being qualified.

Freestyle swimmer Ching Maou Wei became the nation's first male flag bearer at the opening ceremony since 1996.

Among the sports played by the athletes, American Samoa also marked its Olympic return in wrestling after 16 years.

[3] Swimmers have so far achieved qualifying standards in the following events (up to a maximum of 2 swimmers in each event at the Olympic Qualifying Time (OQT), and potentially 1 at the Olympic Selection Time (OST)):[4][5] American Samoa has qualified one quota place.