[3] Swormstedt considered building the museum in Los Angeles, St. Louis, Memphis, and other sites, but eventually settled on Cincinnati, the base of operations for Signs of the Times.

[6] In 2009, the museum added a neon sign from Johnny’s Big Red Grill, once a popular restaurant among Cornell University students.

[8] The new location is part of the Oesterlein Machine Company-Fashion Frocks, Inc. Complex, a National Register of Historic Places building.

[9] The museum opened in its new home in June 2012,[8] and the building displays about 500 signs and artifacts,[10] many of which are on a faux streetscape in a town called "Signville".

[5] Neonworks of Cincinnati moved its business into the museum's new location and features a live exhibit showing visitors how they restore neon signs.