The Inuit were still incensed at the Danish abduction of several people during one of Christian IV's expeditions in 1605, during which Hall served as pilot for John Cunningham.

[3] To the north, the fjord is bounded by the Nasaasaaq ridge, whose massif is spread out over 6 kilometres (3.7 mi) in the west–east direction, constituting the terminal point of a long mountain range extending from the Pingu mountain group halfway between Davis Strait and the Greenland ice sheet (Greenlandic: Sermersuaq).

The range flattens considerably towards the east in the area of Kangaamiut dike swarm north of Kangerlussuaq, due to pressure exerted by the icesheet for long periods in the past.

Royal Arctic Line provides weekly ferry services from Sarfannguit to Sisimiut and Itilleq, a settlement further south on the coast of Davis Strait.

Sisimiut is a port of call for the Arctic Umiaq Line, with connections to Ilulissat and Aasiaat in the Disko Bay region, and to coastal towns in southwestern and southern Greenland.