In 1989, they opened their first major store, located at Plaza del Carmen Mall, in Caguas.

In July 2002, American retail giant Walmart purchased Supermercados Amigo,[1][2][3] in what became a controversial business move.

Claims of unfair competition and monopoly were instantly made by smaller supermarkets, because Amigo would be backed by the strong assets of Walmart.

As part of the agreement made in order for the purchase to take place, various supermarket locations had to be closed (specifically if there was a Walmart or Sam's Club nearby).

On November 5, 2019, Amigo Supermarkets announced a renovation plan on its stores nationwide that would cost $7.8 million US dollars.