As a result, Cotton Gin Port, along the Tombigbee River to the east, was abandoned as businesses and people moved for railroad access.

Believing railroad access to be critical, people from nearby Cotton Gin Port, about 1.5 miles away and located along the Tombigbee River, abandoned their town and moved to Amory.

[6] On the evening of Friday, March 24, 2023, Amory was struck by a fast-moving EF3 tornado, resulting in significant residential damage, as well as multiple injuries and two fatalities.

[9] Amory is in northern Monroe County, on the east side of the valley of the Tombigbee River.

[4] Amory Lock on the Tennessee–Tombigbee Waterway and part of its upstream pool are along the northern edge of the city.

Business sectors in the city include sports equipment manufacturing, wood pulp processing, and the furniture and textile industries.

In honor of its cultural and historical heritage, the city of Amory holds the annual "Railroad Festival" in April in Frisco Park in downtown.

Among other attractions, the Festival includes southern foods—such as fried catfish, barbecue, and apple fritters— rides, arts and crafts, and live music, most notably the local band The Gents who have brought fans out for years with their Motown, Blues Brothers, and classic oldies show.

It returned in 2022, however it was cancelled again in 2023, as Amory was still recovering from the deadly tornado that hit the city on March 24.

In addition to the annual Railroad Festival, Amory held "Entertainment for Education", also known as "Stars Over Mississippi", an event in which a number of celebrities and entertainers hosted a benefit concert to raise funds for local scholarships.

Past performers and attendees included Vince Gill, Dolly Parton, Nell Carter, Sandi Patty, Kathie Lee Gifford, Kathy Ireland, Brad Paisley, Brooks and Dunn, Ray Romano, Tony Danza, Patricia Heaton, Doris Roberts, Whoopi Goldberg, Brad Garrett, and Prince Edward.