Amphixystis anchiala is a moth of the family Tineidae.

It was described by Edward Meyrick in 1909 and is found in Madagascar,[1] Nigeria, and South Africa.

This species has a wingspan of 13 mm, the forewings are dark fuscous with a rather broad whitish-ochreous dorsal stripe from base to apex.

[2] Its appearance is similar to Amphixystis cymataula (Meyrick, 1926) from Zimbabwe, from which it can be distinguished by genitalia examination only.

[3] The larvae have been recorded feeding on Euphorbia resinifera, Citrullus colocynthis (Cucurbitaceae), Dioscorea alata and Dioscorea rotundata (Dioscoreaceae).