Sang Khom (Thai: สร้างคอม, pronounced [sâːŋ kʰɔ̄m]) is a district (amphoe) in northern Udon Thani province, northeastern Thailand.

The district's original name was "Ban Sang Khom" (Thai: บ้านส่างคอม), only slightly different from the modern variation.

"[1] Neighboring districts are (clockwise from the southeast) Ban Dung and Phen of Udon Thani Province and Phon Phisai of Nong Khai province.

[3] The district is divided into six sub-districts (tambons), which are further subdivided into 52 villages (mubans).

There are no municipal (thesaban) areas, and six tambon administrative organizations (TAO).