Amplified magnetic resonance imaging (aMRI)[1][2] is an MRI method that is coupled with video magnification processing methods[3][4] to amplify the subtle spatial variations in MRI scans and to enable better visualization of tissue motion.
aMRI can enable better visualization of tissue motion to aid the in vivo assessment of the biomechanical response in pathology.
It is thought to have potential for helping with diagnosing and monitoring a range of clinical implications in the brain and other organs, including in Chiari Malformation, brain injury, hydrocephalus, other conditions associated with abnormal intracranial pressure, cerebrovascular, and neurodegenerative disease.
This approach can reveal deformations of the brain parenchyma and displacements of arteries due to cardiac pulsatility and CSF flow.
[4] Both video-processing methods use a series of mathematical operations used in image processing known as steerable-pyramid wavelet transformation to amplify motion without the accompanying noise.