[1] During her working life, Flores devoted herself entirely to the business of the mining equipment and construction company Whenhell, of which she was general manager and owner from age 27, from 1979 to 1984.
[2] At age 50, Flores was invited by Manfred Reyes Villa's New Republican Force to participate in the elections, where she won the position of senator for La Paz Department in the Plurinational Legislative Assembly.
[2] During this time, Flores joined the "Transversal Group", a number of senators who had resigned from their respective political parties after the gas conflict.
[2] Four years after leaving office, at age 57, Flores ran for president in the 2009 general election with the United Social Patriotic Movement.
[3][5] In March 2015, at age 63, Flores returned to Bolivian politics, but this time participating in regional elections for the position of mayor of the city of La Paz for the Revolutionary Nationalist Movement.